Treating Depression With Gene Therapy

A new study suggests gene therapy might be key to treating major depression in patients who do not respond to conventional drug treatments. Researchers have discovered that the p11 gene seems to play a major role in depression. By disabling the p11 protein in mice, researchers noticed an increase in depression like symptoms. The proposed gene therapy would help restore the p11 protein within the nucleus accumbens, an area of the brain associated with feelings of reward and pleasure, in order to help reduce depression.

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